I had experienced an usual glitch earlier – a new configuration of Outlook 2013 froze whilst waiting for the Exchange Online setup to complete.

After closing it down, Outlook would not launch. Even after a reboot, Outlook failed to launch.

No luck accessing mail profiles with Mail in Control Panel either, quite bizarre.

A quick regedit got it back up and running, see below:

Run the following command from the CMD prompt ( with Administrator Privileges ):

reg.exe delete HKCU\Software\Microsoft\Office\15.0\Outlook\Profiles\Outlook /f
reg.exe add HKCU\Software\Microsoft\Office\15.0\Outlook\Profiles\Outlook

Alternatively, changing the following key will also yield the same result:

Reset the key under HKEY_CURRENT_USER\Software\Microsoft\Office\15.0\Outlook\ for first run from False to True

Once the above changes were made, I could create a new mail profile and the setup went as planned.